David Sinclair is a professor of genetics at Harvard Medical School and the founder of the Sinclair Lab. He’s the author of the bestselling book Lifespan: Why We Age—and Why We Don’t Have To, as well as a founder of several biotech companies.
Auren and David discuss the potential to expand the average human lifespan by decades. David challenges traditional notions of aging and emphasizes the need to embrace new technologies. They also discuss the benefits and drawbacks of common anti-aging practices like interval training, fasting, and stress reduction.
David shares his thoughts on what longevity medicines and supplements are most beneficial, and how to talk to your doctor about them. He breaks down which health metrics to monitor in treating and preventing aging. Overall, David offers an incredibly optimistic vision for what the future of aging could look like, and the science it will take to get there.
Dr. Nir Barzilai discovered the first “longevity gene” in humans and pioneered key research around the biology of aging. He’s the founding director of the Institute for Aging Research at the Albert Einstein College of Medicine in New York and the author of the book Age Later.
Nir and Auren discuss the most promising studies and treatments in the field of anti-aging research and break down the major takeaways from Nir’s seminal studies on centenarians— why they live longer, and what the rest of us can learn from them.
Nir also explains the role of genetics vs. environment in longevity and makes some data-backed recommendations for anyone who wants to live a longer, healthier life.
You can find Auren Hoffman on Twitter at @auren and Nir Barzilai on Twitter @NirBarzilaiMD
Esther Dyson is an investor, journalist, author, and philanthropist. She is the executive founder of Wellville, a nonprofit project focused on improving equitable wellbeing.
Esther and Auren discuss the structural problems that drive poor wellbeing across modern society. They dive into potential solutions ranging from improving parenting to the role of government.
They also discuss how untapped data about people can potentially revolutionize health and wellness.
You can find Auren Hoffman (CEO of SafeGraph) on Twitter at @auren and Esther Dyson at @edyson